PEA (palmitoylethanolamide) 544-31-0 : A new body own painkiller

A new body own painkiller---

PEA (palmitoylethanolamide) 544-31-0

results confirmed by more than 40 clinical trials.

PROPERTY

Chemicalformula    :     C18H37NO2

CAS NO.   :    544-31-0

Molarmass   :  299.49 g·mol−1

Appearance    :  White crystals

Density    :   910 mg mL−1

Meltingpoint   :59-60 °C(332-333 K)

Boilingpoint   :461.5 °C(735 K)

MAIN FUNCTIONS

anti-inflammatory

anti-nociceptive

neuroprotective

anticonvulsant 

Dr Keppel Hesselink, holding a chair in molecular pharmacologist at the University of Witten/Herdecke in Germany, presented the major breakthrough in chronic pain treatment during the annual neurological congress for Italian neurologists and pain specialists in November  2011. While nearly all painkillers available inhibit pain via the nerve cells, Keppel Hesselink pointed out that a totally different approach via the modulation of the so called glia cells has been overlooked. This approach now has resulted in dramatic improvements of pain in many patients. He expected this treatment to revolutionize the field of pain treatment.

On every nerve cell there are 10 glia cells in our nervous system, and these activated cells are responsible for keeping the body in a chronic pain state. The new compound modulates the glia cells via a body own regulating system and calms these cells, leading to less pain.

The professor pointed out that this compound, palmitoylethanolamide has been tested for safety and efficacy in clinical trials in more than 2000 patients.  Palmitoylethanolamide has also been used already with more than 800,000 patients in Italy, Germany and The Netherlands.

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