Common Fenugreek Seed Extract/ Trigonelline, 4-hydroxyisoleucine/ healthy glucose and cholesterol levels / therapeutic potential for diabetes
What is Fenugreek Seed Extract?
Fenugreek is the seed of Trigonella foenum-graecum L. It is a herb and is widely used as a spice in cooking in Asia and southeastern Europe. It gives a distinct flavor to the food. It is an annual plant with lush leaves. It is grown mostly India, central and South America, and Africa. The seeds are brown in color and are a rich source of proteins, carbohydrates, vitamin A, C, calcium, magnesium, potassium, iron and minerals. The active components of the seeds are trigonelline, 4-hydroxyisoleucine, sotolin, gentianine and carpaine.
Trigonelline Cas #: 535-83-1 Molecule Formula : C7H7NO2
Hydroxyisoleucine Cas # :781658-23-9 Molecule Formula : C6H13NO3
Health Benefits of Fenugreek
Fenugreek seeds are rich source of trigonelline, lysine and l-tryptophan. The seeds also contain a large amount of saponins and fibers that could account for many health benefits of fenugreek.
l Increases Breast Milk - Fenugreek is used as a galactagogue by nursing mothers to increase inadequate breast milk supply. This is evidenced by a study which found that consumption of herbal tea containing fenugreek seeds enhanced breast milk production in mothers and facilitated infant birth weight regain in early postnatal days.
l Lower blood sugar level: It is the 4-hydroxyisoleucine component of the seeds that stimulate the secretion of insulin which lowers blood sugar. It also slows down the digestive process which reduces sugar absorption. It reduces insulin resistance of cells. Recommended dose for diabetes is 500 mg of fenugreek two times a day.
Fenugreek seed extract (Standardized for 1% 2% Trigonelline )
l Reduce Cholesterol level: Research show that regular consumption of Fenugreek lowers cholesterol level. Reduces the level of LDL cholesterol significantly if used for a period of six months. It reduces the risk of heart attack by lowering cholesterol level. The powdered seeds can be taken as capsule or sprinkled over the food.
l Protects from Cancer - Studies have shown that the fibers in fenugreek help prevent certain cancers. For example, researchers at Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, found that fenugreek has estrogenic effects and could be a possible alternative to hormone replacement therapy (HRT). Other studies have shown that saponins and mucilage in fenugreek bind to toxins in the food and flush them out, thus protecting the mucus membrane of the colon from cancers.
l Maintains healthy Testosterone Levels - An Australian study reported significant positive effect of fenugreek on physiological aspects of male libido and also found that it may assist to maintain normal healthy testosterone levels. The study recruited 60 healthy males aged between 25 and 52, without erectile dysfunction and randomized to 2 tablets per day of 600mg Testofen (Fenugreek extract and mineral formulation) or placebo for 6 weeks. The researchers found that Testofen significantly increased sexual arousal and orgasm in the study men.
l Aids Digestion - Fenugreek is said to be an effective heartburn or acid reflux remedy because the mucilage in fenugreek seeds assists in soothing gastrointestinal inflammation, and coating the stomach and intestinal lining. According to a study published in the journal Phytotherapy Research, a 2-week intake of a fenugreek fiber product taken 30 minutes before two meals /day, by subjects with frequent heartburn, diminished heartburn severity. The researchers found that the effects were similar to that of ranitidine at 75mg, twice a day.
Where Can I Buy Fenugreek Seed Extract?
Cima Science Co., Ltd. as an innovator and developer of active ingredients for nutraceutical, pharmaceutical, food, cosmetics industries, can supply fenugreek seed extracts with trusted quality and moderate price. Coa/Spec, samples or other documents and materials will be provided upon your request. Please feel free to contact me: wang@cimasci.com
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