Mulberry Leaf Extract / 1-DNJ / sugar-blocker / beat diabetes & cholesterol

Mulberry Leaf Extract / 1-DNJ / sugar-blocker / beat diabetes & cholesterol

Product Information

【Product Name】Mulberry Leaf Extract

【Brief Introduction】Mulberry Leaf Extract, naturally obtained from dried leaf of Morus alba L. through refine, concentration and drying.

【Ingredients】1-Deoxynojirimycin (1-DNJ)

                  Mulberry Leaf polysaccharide

                  Mulberry Leaf flavone

                  5:1 ; 10:1 ; 20:1

Active Ingredient : 1-Deoxynojirimycin (1-DNJ)

Cas # : 19130-96-2

Molecule formula : C₆H₁₃NO₄

Molecule weight : 163.17

Molecule structure :

Product Description

Mulberry leaves have a high nutrient and antioxidant profile. They contain a wide variety of nutrients, including proteins, sugars, polyphenols, flavonoids (iso-quercitrin), steroids, triterpenes, vitamins, and minerals.

Research has been focused on the use of muberry leaf extract as a significant medicine for type 2 diabetes and atherosclerosis, as well as other health benefits.

ü Control Blood Sugar Levels

ü Block Metabolism of Sugar

ü Promotes Weight Loss

ü Lowers Cholesterol Levels

ü Prevent Diabetes

ü Insulin sensitivity and improving insulin resistance

Inhibiting activities against a-glycosidase

Where Can I Buy Mulberry Leaf Extract?

Cima Science Co., Ltd. as an innovator and developer of active ingredients for nutraceutical, pharmaceutical, food, cosmetics industries, can supply mulberry leaf extracts with trusted quality and moderate price. Coa/Spec, samples or other documents and materials will be provided upon your request. Please feel free to contact me: wang@cimasci.com

Common Fenugreek Seed Extract/ Trigonelline, 4-hydroxyisoleucine/ healthy glucose and cholesterol levels / therapeutic potential for diabetes

Common Fenugreek Seed Extract/ Trigonelline, 4-hydroxyisoleucine/ healthy glucose and cholesterol levels / therapeutic potential for diabetes

What is Fenugreek Seed Extract?

Fenugreek is the seed of Trigonella foenum-graecum L. It is a herb and is widely used as a spice in cooking in Asia and southeastern Europe. It gives a distinct flavor to the food. It is an annual plant with lush leaves. It is grown mostly India, central and South America, and Africa. The seeds are brown in color and are a rich source of proteins, carbohydrates, vitamin A, C, calcium, magnesium, potassium, iron and minerals. The active components of the seeds are trigonelline, 4-hydroxyisoleucine, sotolin, gentianine and carpaine.

   Trigonelline  Cas #: 535-83-1 Molecule Formula : C7H7NO2

Hydroxyisoleucine  Cas # :781658-23-9 Molecule Formula : C6H13NO3

Health Benefits of Fenugreek

Fenugreek seeds are rich source of trigonelline, lysine and l-tryptophan. The seeds also contain a large amount of saponins and fibers that could account for many health benefits of fenugreek.

l Increases Breast Milk - Fenugreek is used as a galactagogue by nursing mothers to increase inadequate breast milk supply. This is evidenced by a study which found that consumption of herbal tea containing fenugreek seeds enhanced breast milk production in mothers and facilitated infant birth weight regain in early postnatal days.

l Lower blood sugar level: It is the 4-hydroxyisoleucine component of the seeds that stimulate the secretion of insulin which lowers blood sugar. It also slows down the digestive process which reduces sugar absorption. It reduces insulin resistance of cells. Recommended dose for diabetes is 500 mg of fenugreek two times a day.

      

 Fenugreek seed extract (Standardized for 1% 2% Trigonelline )

l Reduce Cholesterol level: Research show that regular consumption of Fenugreek lowers cholesterol level. Reduces the level of LDL cholesterol significantly if used for a period of six months. It reduces the risk of heart attack by lowering cholesterol level. The powdered seeds can be taken as capsule or sprinkled over the food.

l Protects from Cancer - Studies have shown that the fibers in fenugreek help prevent certain cancers. For example, researchers at Rajiv Gandhi Center for Biotechnology, Thiruvananthapuram, found that fenugreek has estrogenic effects and could be a possible alternative to hormone replacement therapy (HRT). Other studies have shown that saponins and mucilage in fenugreek bind to toxins in the food and flush them out, thus protecting the mucus membrane of the colon from cancers.

l Maintains healthy Testosterone Levels - An Australian study reported significant positive effect of fenugreek on physiological aspects of male libido and also found that it may assist to maintain normal healthy testosterone levels. The study recruited 60 healthy males aged between 25 and 52, without erectile dysfunction and randomized to 2 tablets per day of 600mg Testofen (Fenugreek extract and mineral formulation) or placebo for 6 weeks. The researchers found that Testofen significantly increased sexual arousal and orgasm in the study men.

l Aids Digestion - Fenugreek is said to be an effective heartburn or acid reflux remedy because the mucilage in fenugreek seeds assists in soothing gastrointestinal inflammation, and coating the stomach and intestinal lining.  According to a study published in the journal Phytotherapy Research, a 2-week intake of a fenugreek fiber product taken 30 minutes before two meals /day, by subjects with frequent heartburn, diminished heartburn severity. The researchers found that the effects were similar to that of ranitidine at 75mg, twice a day.

Where Can I Buy Fenugreek Seed Extract?

Cima Science Co., Ltd. as an innovator and developer of active ingredients for nutraceutical, pharmaceutical, food, cosmetics industries, can supply fenugreek seed extracts with trusted quality and moderate price. Coa/Spec, samples or other documents and materials will be provided upon your request. Please feel free to contact me: wang@cimasci.com

White Kidney Bean Extract / Alpha-AI / carbohydrate blocker / loss weight naturally

Calcium β-hydroxy-β-methylbutyrate (CaHMB) / Sports Nutritional Supplement

HMB chemical profile
HMB (ß-hydroxy-ß-methylbutyrate) is a metabolite of leucine, a branched-chain essential
amino acid consumed from dietary sources. Leucine regulates protein synthesis and helps
maintain nitrogen balance, an indicator of the availability of protein for the body’s use.
HMB is the active metabolite of leucine that regulates protein synthesis in muscle cells.
HMB has been shown to inhibit muscle proteolysis and modulate protein turnover.

Chemistry
The chemical formula of HMB is C5H10O3; its molecular weight is 118.13. HMB
is produced commercially by organic chemical synthesis and is supplied as a calcium salt:
CaHMB monohydrate (Ca(C5H9O3)2-H2O).

HMB (ß-hydroxy-ß-methylbutyrate) is a naturally occurring leucine metabolite that rebuilds
lean body mass (LBM) as well as muscle strength. Maintaining LBM, and muscle mass
in particular, is essential to support whole-body protein metabolism, physical strength,
immune function, skin integrity, wound healing, and organ function. LBM loss increases
risk for physical disability, compromises immune function, impairs wound healing, and
increases mortality in the elderly, in people with chronic illness, and in critically ill patients.
HMB addresses underlying factors that alter protein metabolism and helps maintain and
rebuild LBM by stabilizing the muscle membrane and by improving the balance of protein
degradation and protein synthesis within the muscle cell.

The clinical benefits of HMB, alone and as part of a nutrient mixture containing arginine
and glutamine or lysine, have been demonstrated in controlled studies involving elderly
volunteers, patients with LBM loss due to AIDS or cancer, and critically ill patients. Patients
in these studies who received HMB or an HMB–amino acid mixture showed shifts in body
composition with gains in LBM and losses in body fat.
• Elderly women taking HMB plus arginine and lysine had substantial LBM gains
accompanied by significant improvements in muscle strength and functionality
• In elderly volunteers adding HMB to a 5-day weight-resistance exercise program,
substantial increases in LBM were accompanied by significant reductions in body fat
• Patients with LBM loss due to stage IV solid tumors saw significant improvements in
LBM with HMB/ARG/GLN
• In patients with LBM loss due to AIDS, HMB/ARG/GLN provided significant LBM and
body weight gains and significant immune benefits
• HMB improved protein metabolism in critical care patients hospitalized due to trauma
or chronic obstructive pulmonary disease
HMB, at the recommended dose of 3 g daily, has an established profile of safety and
tolerability in the elderly as well as in people with serious illness.

Where to buy CaHMB:

Cima Science is a Chinese and creative company, dedicated to developing, manufacturing and marketing innovative botanical active ingredients, nutritional raw materials for the food, beverage nutraceutical, pharmaceutical, cosmetic and feed industries.

CaHMB and other nutritional raw materials are available here, if any interest, please contact me freely. wang@cimasci.com  

alpha-GPC / improve memory / 28319-77-9

Strontium Citrate / CAS#: 813-97-8 / for Osteoporosis / strong your bone

        Strontium Citrate
Strontium is a trace element found in seawater and soil. The main dietary source of strontium is seafood. Foods with lesser amounts of strontium include whole milk, wheat bran, meat, poultry, and root vegetables.
Strontium is chemically similar to calcium. It appears to play a role in the formation of new bone while slowing the breakdown of old bone, and thus may influence bone density. There is some evidence that women with osteoporosis may not absorb strontium as they should.

Chemical Profile
• CAS#: 813-97-8
• Molecular Weight: 640.86
• Molecular Formula: (C6H5O7)2Sr3
• Other Names: Strontium 2-hydroxy-1,2,3-propanetricarboxylate; Tristrontium dicitrate

Strontium Increases Bone Mass Density
Strontium supplementation has been demonstrated to be a welltolerated and effective means of preventing bone loss. 

In 2004, a double-blinded, placebo controlled study published in The New England Journal of Medicine aimed to evaluate the efficacy of strontium on helping to prevent structural damage and bone fragility. 

Over a three- year period, strontium supplementation reduced the risk of fracture by 41%. This reduction in risk was closely tied to the increase in bone mineral density in the lumbar spine and femoral neck. The occurrence of adverse side effects was low and reported equally among the treatment and placebo groups, further indicating the safe use of daily strontium supplements.

Bone Support

Prevention of Osteoporosis

Promoters of Healthy Teeth and Bones

Increase in bone mineral density (BMD)

........

Research by pharmaceutical companies has shown that strontium can improve bone density by 8-14% when combined with daily supplements of 1,500 mg of calcium and 800 IUs of vitamin D.

If any interest about this product, please feel free to contact me ： 

Mail : wang@cimasci.com  

skype : Vinnie2627  

Oxaloacetic acid / oxalacetic acid / OAA / 328-42-7

Oxaloacetic acid / oxalacetic acid / OAA / 328-42-7

Oxaloacetic acid (also known as oxalacetic acid) is a crystalline organic compound with the chemical formula HO2CC(O)CH2CO2H. Oxaloacetic acid, in the form of its conjugate base oxaloacetate, is a metabolic intermediate in many processes that occur in animals.

Product name : Oxaloacetic acid

Synonyms : OAA, Oxobutanedioic acid, benaGene , Oxaloacetic acid, Oxalacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid, Oxaloacetate，3-carboxy-3-oxopropanoic acid

CAS :  328-42-7

Molecular Formula :  C4H4O5

Specifications :  98%

Appearance/color :  White crystalline powder

Function :  for anti- aging & fatigue

Here are a few of the many studies that have been published on supplemental oxaloacetic acid:

“Modification of the NAD+/NADH Ratio Via Oxaloacetic Acid Supplementation to Mimic Calorie Restriction Metabolic Pathways and Increase Lifespan”

Alan Cash, Anti-Aging Therapeutics Volume XII, American Academy of Anti-Aging Medicine, December 2010

“Oxaloacetate Enhances Resistance to Fatigue in In vitro Mouse Soleus Muscle”

Daniel Hogan, Leonardo Nogueira, Michael C. Hogan, FACSM

Division of Physiology, Department of Medicine, UCSD, La Jolla, CA presented at the American College of Sports Medicine, 2010

“Acute Oxaloacetate Exposure Enhances Resistance to Fatigue in in vitro Mouse Soleus Muscle”

Leonardo Nogueira, Daniel Hogan and Michael C Hogan

 Division of Physiology, Department of Medicine, UCSD, La Jolla, CA, April 2011, The Federation of American Societies for Experimental Biology

“Oxaloacetic Acid Supplementation as a Mimic of Calorie Restriction” 

“Oxaloacetate Increases Lifespan”, which documented a 25% increase in lifespan using oxaloacetate supplementation.

If you have any interest about this product, please contact :

wang@cimasci.com

skype : vinnie2627