2016年5月27日星期五
2016年5月23日星期一
Strontium Citrate / CAS#: 813-97-8 / for Osteoporosis / strong your bone
Strontium Citrate
Strontium is a trace element found in seawater and soil. The main dietary source of strontium is seafood. Foods with lesser amounts of strontium include whole milk, wheat bran, meat, poultry, and root vegetables.
Strontium is chemically similar to calcium. It appears to play a role in the formation of new bone while slowing the breakdown of old bone, and thus may influence bone density. There is some evidence that women with osteoporosis may not absorb strontium as they should.
Chemical Profile
• CAS#: 813-97-8
• Molecular Weight: 640.86
• Molecular Formula: (C6H5O7)2Sr3
• Other Names: Strontium 2-hydroxy-1,2,3-propanetricarboxylate; Tristrontium dicitrate
Strontium is a trace element found in seawater and soil. The main dietary source of strontium is seafood. Foods with lesser amounts of strontium include whole milk, wheat bran, meat, poultry, and root vegetables.
Strontium is chemically similar to calcium. It appears to play a role in the formation of new bone while slowing the breakdown of old bone, and thus may influence bone density. There is some evidence that women with osteoporosis may not absorb strontium as they should.
Chemical Profile
• CAS#: 813-97-8
• Molecular Weight: 640.86
• Molecular Formula: (C6H5O7)2Sr3
• Other Names: Strontium 2-hydroxy-1,2,3-propanetricarboxylate; Tristrontium dicitrate
Strontium Increases Bone Mass Density
Strontium supplementation has been demonstrated to be a welltolerated and effective means of preventing bone loss.
Strontium supplementation has been demonstrated to be a welltolerated and effective means of preventing bone loss.
In 2004, a double-blinded, placebo controlled study published in The New England Journal of Medicine aimed to evaluate the efficacy of strontium on helping to prevent structural damage and bone fragility.
Over a three- year period, strontium supplementation reduced the risk of fracture by 41%. This reduction in risk was closely tied to the increase in bone mineral density in the lumbar spine and femoral neck. The occurrence of adverse side effects was low and reported equally among the treatment and placebo groups, further indicating the safe use of daily strontium supplements.
Bone Support
Prevention of Osteoporosis
Promoters of Healthy Teeth and Bones
Increase in bone mineral density (BMD)
........
Research by pharmaceutical companies has shown that strontium can improve bone density by 8-14% when combined with daily supplements of 1,500 mg of calcium and 800 IUs of vitamin D.
If any interest about this product, please feel free to contact me ：
Mail : wang@cimasci.com
skype : Vinnie2627
2016年5月17日星期二
Oxaloacetic acid / oxalacetic acid / OAA / 328-42-7
Oxaloacetic acid / oxalacetic acid / OAA / 328-42-7
Oxaloacetic acid (also known as oxalacetic acid) is a crystalline organic compound with the chemical formula HO2CC(O)CH2CO2H. Oxaloacetic acid, in the form of its conjugate base oxaloacetate, is a metabolic intermediate in many processes that occur in animals.
Product name : Oxaloacetic acid
Synonyms : OAA, Oxobutanedioic acid, benaGene , Oxaloacetic acid, Oxalacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid, Oxaloacetate，3-carboxy-3-oxopropanoic acid
CAS : 328-42-7
Molecular Formula : C4H4O5
Specifications : 98%
Appearance/color : White crystalline powder
Function : for anti- aging & fatigue
Here are a few of the many studies that have been published on supplemental oxaloacetic acid:
“Modification of the NAD+/NADH Ratio Via Oxaloacetic Acid Supplementation to Mimic Calorie Restriction Metabolic Pathways and Increase Lifespan”
Alan Cash, Anti-Aging Therapeutics Volume XII, American Academy of Anti-Aging Medicine, December 2010
“Oxaloacetate Enhances Resistance to Fatigue in In vitro Mouse Soleus Muscle”
Daniel Hogan, Leonardo Nogueira, Michael C. Hogan, FACSM
Division of Physiology, Department of Medicine, UCSD, La Jolla, CA presented at the American College of Sports Medicine, 2010
“Acute Oxaloacetate Exposure Enhances Resistance to Fatigue in in vitro Mouse Soleus Muscle”
Leonardo Nogueira, Daniel Hogan and Michael C Hogan
Division of Physiology, Department of Medicine, UCSD, La Jolla, CA, April 2011, The Federation of American Societies for Experimental Biology
“Oxaloacetic Acid Supplementation as a Mimic of Calorie Restriction”
“Oxaloacetate Increases Lifespan”, which documented a 25% increase in lifespan using oxaloacetate supplementation.
If you have any interest about this product, please contact :
wang@cimasci.com
skype : vinnie2627
2016年4月21日星期四
Palmitoylethanolamide (PEA) --- Your Trusted Pain Killer
Palmitoylethanolamide (PEA)
--- Your Trusted Pain Killer
Palmitoylethanolamide (PEA) is a body-own fatty acid compound, and is produced by our own living cells to restore balance in chronic pain and chronic inflammation. Its anti-inflammatory and painkilling properties have been established over many decades since its first discovery in 1957.
PEA also has the chemical name n- (2-hydroxyethyl)hexadecanamide.
PEA has been demonstrated in recent trials to decrease pain in diabetic neuropathic pain, zoster pain lumbosacral pain (sciatic pain), carpal tunnel syndrome and nervus medianus compression pain, endometriosis pains, menstrual pains, etc. It has been proven to be effective and safe in many different disorders, from chronic pains up to flu and common cold, due to its intrinsic anti-inflammatory and analgesic properties. Now PEA can also be considered as a breakthrough natural therapy for flu and common colds.
2016年4月18日星期一
Stearoylethanolamide exerts anorexic effects in mice
Stearoylethanolamide exerts anorexic effects in mice via down-regulation of liver stearoyl-coenzyme A desaturase-1 mRNA expression.
Given the recent demonstration that oleoylethanolamide (OEA), a cannabinoid receptor-inactive N-acylethanolamine, decreases food intake by activating the nuclear receptor PPARalpha (peroxisome proliferator-activated receptor alpha) in the periphery, we here evaluated the effects of both saturated and unsaturated C18 N-acylethanolamides (C18:0; C18:1; C18:2) in mice feeding behavior after overnight starvation.
Our results show stearoylethanolamide (SEA, C18:0) exerts, unlike other unsaturated C18 homologs, a marked dose-dependent anorexic effect evident already at 2 h after its intraperitoneal administration. In addition, oral administration of SEA (25 mg/kg) was also effective in reducing food consumption, an effect ascribed to the molecule itself and not to its catabolites.
Moreover, although the anorexic response to oral administered SEA was not associated with changes in the levels of various hematochemical parameters (e.g., glucose, cholesterol, triglycerides, leptin) nor in liver mRNA expression of peroxisome proliferator-activated receptors (PPARs) including PPARalpha, the anorexic effect of SEA was interestingly accompanied by a reduction in liver stearoyl-CoA desaturase-1 (SCD-1) mRNA expression.
As SCD-1 has been recently proposed as a molecular target for the treatment of obesity, the novel observation provided here that SEA reduces food intake in mice in a structurally selective manner, in turn, correlated with downregulation of liver SCD-1 mRNA expression, has the potential of providing new insights on a class of lipid mediators with suitable properties for the pharmacological treatment of over-eating dysfunctions.
Given the recent demonstration that oleoylethanolamide (OEA), a cannabinoid receptor-inactive N-acylethanolamine, decreases food intake by activating the nuclear receptor PPARalpha (peroxisome proliferator-activated receptor alpha) in the periphery, we here evaluated the effects of both saturated and unsaturated C18 N-acylethanolamides (C18:0; C18:1; C18:2) in mice feeding behavior after overnight starvation.
Our results show stearoylethanolamide (SEA, C18:0) exerts, unlike other unsaturated C18 homologs, a marked dose-dependent anorexic effect evident already at 2 h after its intraperitoneal administration. In addition, oral administration of SEA (25 mg/kg) was also effective in reducing food consumption, an effect ascribed to the molecule itself and not to its catabolites.
Moreover, although the anorexic response to oral administered SEA was not associated with changes in the levels of various hematochemical parameters (e.g., glucose, cholesterol, triglycerides, leptin) nor in liver mRNA expression of peroxisome proliferator-activated receptors (PPARs) including PPARalpha, the anorexic effect of SEA was interestingly accompanied by a reduction in liver stearoyl-CoA desaturase-1 (SCD-1) mRNA expression.
As SCD-1 has been recently proposed as a molecular target for the treatment of obesity, the novel observation provided here that SEA reduces food intake in mice in a structurally selective manner, in turn, correlated with downregulation of liver SCD-1 mRNA expression, has the potential of providing new insights on a class of lipid mediators with suitable properties for the pharmacological treatment of over-eating dysfunctions.
2016年4月17日星期日
Stearoyl ethanolamide (SEA) 111-57-9 appetite control weight management
Stearoyl ethanolamide
CAS Number 111-57-9 Molecular Formula: C20H41NO2
Molecular Weight 327.55
Purity: >98%
Description
Stearoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called anandamides. Stearoyl ethanolamide is the most prolific of several fatty acid ethanolamides produced by the PLD hydrolysis of murine neuroblastoma cell membrane phospholipids. The specific role of stearoyl ethanolamide in the cannabinergic system is still to be elucidated.
Function
Weight management; appetite suppressant; lose weight
Application
Sports nutrition , nutritional supplements, bodybuilding
Where can I find
Cima Science Co., Ltd. has long been devoted to developing, manufacturing and marketing innovative botanical active ingredients, nutritional raw materials for the food, beverage nutraceutical, pharmaceutical, cosmetic and feed industries.
Regarding WEIGHT LOSS products, We are in good position of producing and supplying :
Oleoylethanolamide 111-58-0
Stearoyl Ethanolamide 111-57-9
Stearoyl Vanillylamide 58493-50-8
2016年4月13日星期三
Essential Oil Components from Nigella sativa Seed / Black Cumin
Identification of
Essential Oil Components
from Nigella sativa Seed
by Gas Chromatography-mass Spectroscopy
Abstract: The volatile oils from the seed of Nigella sativa were obtained by steam distillation. Gas chromatography-mass spectrometry was used to identify the components. Nine volatile oils were identified and 2-methyl-5(1-methyl ethyl)-Bicyclo[3.1.0]hex-2-ene was the major constituent (62.28%) while alphapinene was the minor (2.28%).
Chemical composition of the volatile oil of Nigella sativa
Conclusion: The ingredients obtained from this study indicate that the oil can be fully utilized for the manufacture of perfumery products, antimicrobial and antiseptic agents.
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